APBB1

Across TCGA patient cohorts, APBB1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,444 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APBB1-associated genes across cancer lineages are DLC1, HINT2P1, and TSPOAP1. Each is linked with APBB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both APBB1-to-partner and partner-to-APBB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APBB1 versus DLC1 in CCRCC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB1→partner) and Y-score (partner→APBB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DLC1 →	+0.921	+0.274	<.001	<.001	3	6
UCEC	HINT2P1 →	+0.684	+0.393	.002	<.001	3	6
OV	TSPOAP1 →	+0.709	+0.319	.006	.002	3	6
CCRCC	ZDHHC15 →	+0.821	+0.390	<.001	<.001	3	5
LUAD	CDC20 →	-1.391	-0.251	<.001	<.001	3	5
UCEC	CNTN4 →	+0.882	+0.595	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,444 associations by consensus.

APBB1 vs DLC1 — CCRCC

Explore this scatter interactively →