APBB1

Across TCGA cell cohorts, APBB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,418 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible APBB1-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and RNA splicing, via transesterification reactions. Each is linked with APBB1 in more than 13 cancer types. Because this analysis shows association rather than direction, both APBB1-to-partner and partner-to-APBB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by APBB1-low versus APBB1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APBB1→partner) and Y-score (partner→APBB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.145	+2.684	<.001	<.001	3	14
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.145	+2.647	<.001	<.001	3	13
STOMACH	RNA splicing, via transesterification reactions →	+0.066	+2.147	.001	.001	3	13
STOMACH	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.065	+2.002	.002	.002	3	13
STOMACH	mRNA splicing, via spliceosome →	+0.065	+2.002	.002	.002	3	13
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.107	+2.034	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,418 associations by consensus.

Negative regulation of myoblast fusion by APBB1 expression — STOMACH

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