APBA3

Across TCGA cell cohorts, APBA3 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible APBA3-associated genes across cancer lineages are OR13C3, ACOD1, and BARHL1. Each is linked with APBA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both APBA3-to-partner and partner-to-APBA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13C3 grouped by APBA3-low versus APBA3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBA3→partner) and Y-score (partner→APBA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR13C3 →	+0.018	+4.887	<.001	.009	3	2
STOMACH	ACOD1 →	+0.006	+5.285	<.001	.003	3	1
BLOOD_Lymphoma	BARHL1 →	+0.031	+3.724	<.001	.002	3	1
BLOOD_Lymphoma	CSTL1 →	+0.254	+3.130	<.001	.006	3	1
BLOOD_Lymphoma	CFHR4 →	+0.152	+3.343	<.001	<.001	3	1
BLOOD_Lymphoma	DSG1 →	+0.543	+2.934	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

OR13C3 by APBA3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →