APBA2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, APBA2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,998 significant associations in total. GBM shows the largest number of these associations.

The most reproducible APBA2-associated genes across cancer lineages are KIF3C, OCA2, and HRK. Each is linked with APBA2 in more than 2 cancer types. Because this analysis shows association rather than direction, both APBA2-to-partner and partner-to-APBA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, APBA2 versus KIF3C in OV, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (APBA2→partner) and Y-score (partner→APBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVKIF3C →+0.885+0.435.003.00533
BRCAOCA2 →+1.227+1.031<.001<.00133
GBMHRK →+1.066+0.359<.001<.00133
GBMARMH4 →+0.845+0.359<.001<.00133
UCECFAM166C →+0.861+0.396<.001<.00133
BRCAOLFM2 →+0.833+0.610.005<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,998 associations by consensus.

APBA2 vs KIF3C — OV

Per-sample scatter of APBA2 vs KIF3C in OV (Pearson r = 0.50).

Explore this scatter interactively →

Exploration