APBA2

Across TCGA cell cohorts, APBA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,162 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible APBA2-associated GO terms across cancer lineages are DNA-templated transcription initiation, tRNA transcription, and Transcription initiation at RNA polymerase II promoter. Each is linked with APBA2 in more than 14 cancer types. Because this analysis shows association rather than direction, both APBA2-to-partner and partner-to-APBA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by APBA2-low versus APBA2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (APBA2→partner) and Y-score (partner→APBA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DNA-templated transcription initiation →	+0.081	+2.722	.001	.001	3	15
LUNG_NSCLC_LUSC	tRNA transcription →	+0.121	+2.551	.002	.002	3	13
URINARY_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.068	+1.964	<.001	.007	2	13
LIVER	Protein-DNA complex organization →	+0.042	+1.881	.004	<.001	3	11
OESOPHAGUS	tRNA transcription by RNA polymerase III →	+0.118	+2.512	<.001	<.001	2	12
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.136	+2.064	.003	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,162 associations by consensus.

DNA-templated transcription initiation by APBA2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →