AP5S1

Across TCGA patient cohorts, AP5S1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,431 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP5S1-associated genes across cancer lineages are TLR7, DOCK8, and SELPLG. Each is linked with AP5S1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP5S1-to-partner and partner-to-AP5S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP5S1 versus TLR7 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5S1→partner) and Y-score (partner→AP5S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TLR7 →	+0.811	+0.249	.002	<.001	3	6
BRCA	DOCK8 →	+0.602	+0.176	.001	.004	3	4
GBM	SELPLG →	+0.541	+0.182	.004	<.001	3	4
BRCA	TMEM86A →	+1.278	+0.267	<.001	<.001	3	4
GBM	MS4A7 →	+0.880	+0.193	.006	.009	3	4
HNSC	RNASE6 →	+0.833	+0.253	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,431 associations by consensus.

AP5S1 vs TLR7 — GBM

Explore this scatter interactively →