AP5S1

Across TCGA patient cohorts, AP5S1 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP5S1-associated genes across cancer lineages are YB-1 and Ku80. Each is linked with AP5S1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AP5S1-to-partner and partner-to-AP5S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, YB-1 grouped by AP5S1-low versus AP5S1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5S1→partner) and Y-score (partner→AP5S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YB-1 →	+0.227	+2.833	.019	.035	2	1
UCEC	Ku80 →	+0.297	+2.820	.040	.036	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

YB-1 by AP5S1 expression — UCEC

Explore this box plot interactively →