AP5S1

Across TCGA cell cohorts, AP5S1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,631 significant associations in total. CNS shows the largest number of these associations.

The most reproducible AP5S1-associated GO terms across cancer lineages are Positive regulation of protein localization to endoplasmic reticulum, Regulation of protein localization to endoplasmic reticulum, and Regulation of peroxisome organization. Each is linked with AP5S1 in more than 15 cancer types. Because this analysis shows association rather than direction, both AP5S1-to-partner and partner-to-AP5S1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to endoplasmic reticulum grouped by AP5S1-low versus AP5S1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5S1→partner) and Y-score (partner→AP5S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of protein localization to endoplasmic reticulum →	+0.126	+0.873	<.001	<.001	3	16
KIDNEY	Regulation of protein localization to endoplasmic reticulum →	+0.122	+0.651	<.001	<.001	3	15
STOMACH	Regulation of peroxisome organization →	+0.220	+1.145	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Lysosome organization →	+0.065	+0.830	.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Lytic vacuole organization →	+0.065	+0.830	.001	.001	3	14
STOMACH	Vacuole organization →	+0.052	+0.660	<.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,631 associations by consensus.

Positive regulation of protein localization to endoplasmic reticulum by AP5S1 expression — SKIN

Explore this box plot interactively →