AP5M1

Across TCGA patient cohorts, AP5M1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,822 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP5M1-associated genes across cancer lineages are LILRB5, TMC8, and KCNE1. Each is linked with AP5M1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP5M1-to-partner and partner-to-AP5M1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP5M1 versus LILRB5 in CCRCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5M1→partner) and Y-score (partner→AP5M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LILRB5 →	+0.694	+0.192	<.001	.001	3	6
LUAD	TMC8 →	+0.582	+0.196	<.001	<.001	3	5
LSCC	KCNE1 →	+0.490	+0.169	<.001	<.001	3	4
UCEC	PTGDS →	+0.685	+0.159	<.001	<.001	3	4
LUAD	NAAA →	+0.332	+0.114	<.001	.002	3	4
CCRCC	IGSF6 →	+0.590	+0.293	.003	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,822 associations by consensus.

AP5M1 vs LILRB5 — CCRCC

Explore this scatter interactively →