AP5M1

Across TCGA patient cohorts, AP5M1 mutation is significantly associated with the RNA expression of many other genes, with 2,078 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP5M1-associated genes across cancer lineages are LINC01072, B3GALNT2P1, and NPLP1. Each is linked with AP5M1 in more than 2 cancer types. Because this analysis shows association rather than direction, both AP5M1-to-partner and partner-to-AP5M1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01072 grouped by AP5M1-low versus AP5M1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5M1→partner) and Y-score (partner→AP5M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	LINC01072 →	+0.088	+5.305	<.001	.003	3	3
READ	B3GALNT2P1 →	+0.160	+5.421	<.001	.005	3	2
READ	NPLP1 →	+0.529	+5.421	<.001	.005	3	2
READ	LINC00458 →	+0.037	+5.039	<.001	.008	3	2
READ	UBE2V1P6 →	+0.199	+5.925	<.001	.002	3	2
READ	RN7SL266P →	+0.283	+6.257	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,078 associations by consensus.

LINC01072 by AP5M1 expression — LIHC

Explore this box plot interactively →