AP5B1

Across TCGA patient cohorts, AP5B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,228 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP5B1-associated proteins across cancer lineages are RRBP1, SMCHD1, and MCM2. Each is linked with AP5B1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AP5B1-to-partner and partner-to-AP5B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP5B1 versus RRBP1 in BRCA, with a Pearson correlation of -0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5B1→partner) and Y-score (partner→AP5B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RRBP1 →	-0.388	-0.538	<.001	<.001	3	4
HNSC	SMCHD1 →	+0.314	+0.567	<.001	<.001	3	4
LSCC	MCM2 →	+0.425	+0.366	.002	.001	3	4
UCEC	PURA →	-0.250	-0.524	.006	<.001	3	3
UCEC	CALHM5_S238 →	-0.837	-0.933	.001	<.001	3	3
CCRCC	CEP128 →	-0.294	-0.329	.009	.009	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,228 associations by consensus.

AP5B1 vs RRBP1 — BRCA

Explore this scatter interactively →