AP5B1

Across TCGA patient cohorts, AP5B1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,013 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP5B1-associated genes across cancer lineages are C1QC, SIGLEC1, and C1QA. Each is linked with AP5B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP5B1-to-partner and partner-to-AP5B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP5B1 versus C1QC in LUAD, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5B1→partner) and Y-score (partner→AP5B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	C1QC →	+0.947	+0.177	<.001	<.001	3	6
LUAD	SIGLEC1 →	+0.962	+0.178	<.001	<.001	3	5
BRCA	C1QA →	+0.892	+0.200	.002	.001	3	5
LSCC	OSCAR →	+0.810	+0.252	<.001	<.001	3	4
GBM	MS4A4E →	+0.900	+0.244	<.001	<.001	3	4
PDAC	NCF2 →	+0.591	+0.286	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,013 associations by consensus.

AP5B1 vs C1QC — LUAD

Explore this scatter interactively →