AP5B1

Across TCGA cell cohorts, AP5B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,111 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AP5B1-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Regulation of pattern recognition receptor signaling pathway, and Negative regulation of calcium ion export across plasma membrane. Each is linked with AP5B1 in more than 15 cancer types. Because this analysis shows association rather than direction, both AP5B1-to-partner and partner-to-AP5B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by AP5B1-low versus AP5B1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP5B1→partner) and Y-score (partner→AP5B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.224	+0.819	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of pattern recognition receptor signaling pathway →	+0.084	+1.248	<.001	<.001	3	15
BREAST	Negative regulation of calcium ion export across plasma membrane →	+0.088	+0.956	.002	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.076	+1.070	<.001	<.001	3	14
SKIN	Vacuole organization →	+0.052	+1.064	<.001	<.001	3	14
SKIN	Lysosome organization →	+0.059	+0.993	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,111 associations by consensus.

Pre-mRNA catabolic process by AP5B1 expression — BONE

Explore this box plot interactively →