AP4E1

Across TCGA patient cohorts, AP4E1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,577 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP4E1-associated proteins across cancer lineages are DDX28, RTF1, and FAM98B. Each is linked with AP4E1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AP4E1-to-partner and partner-to-AP4E1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP4E1 versus DDX28 in COAD, with a Pearson correlation of -0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP4E1→partner) and Y-score (partner→AP4E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DDX28 →	-0.460	-0.373	<.001	<.001	3	4
LSCC	RTF1 →	+0.358	+0.460	<.001	<.001	3	4
GBM	FAM98B →	+0.246	+0.344	.006	<.001	3	4
COAD	TBRG4 →	-0.401	-0.258	<.001	<.001	3	4
OV	TP53BP1_S598 →	+1.518	+0.828	.002	.001	3	4
COAD	LRPPRC →	-0.535	-0.486	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,577 associations by consensus.

AP4E1 vs DDX28 — COAD

Explore this scatter interactively →