AP4B1

Across TCGA patient cohorts, AP4B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,459 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AP4B1-associated proteins across cancer lineages are TRIM33, RSBN1, and DR1. Each is linked with AP4B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP4B1-to-partner and partner-to-AP4B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP4B1 versus TRIM33 in GBM, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP4B1→partner) and Y-score (partner→AP4B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM33 →	+0.352	+0.320	<.001	<.001	3	6
BRCA	RSBN1 →	+0.366	+0.555	<.001	<.001	3	5
GBM	DR1 →	+0.383	+0.300	<.001	<.001	3	5
BRCA	MIER1 →	+0.192	+0.386	<.001	<.001	3	5
GBM	RBBP4 →	+0.386	+0.279	<.001	<.001	3	4
GBM	RBM15 →	+0.256	+0.217	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,459 associations by consensus.

AP4B1 vs TRIM33 — GBM

Explore this scatter interactively →