AP3S2

Across TCGA cell cohorts, AP3S2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,249 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AP3S2-associated GO terms across cancer lineages are Synaptic vesicle coating, Regulation of heterochromatin organization, and Synaptic vesicle budding from presynaptic endocytic zone membrane. Each is linked with AP3S2 in more than 13 cancer types. Because this analysis shows association rather than direction, both AP3S2-to-partner and partner-to-AP3S2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Synaptic vesicle coating grouped by AP3S2-low versus AP3S2-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3S2→partner) and Y-score (partner→AP3S2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Synaptic vesicle coating →	+0.189	+0.991	.001	.001	2	14
SOFT_TISSUE	Regulation of heterochromatin organization →	+0.094	+1.035	<.001	<.001	3	12
BLOOD_Lymphoma	Synaptic vesicle budding from presynaptic endocytic zone membrane →	+0.122	+1.006	.001	.003	3	11
BONE	Protein linear polyubiquitination →	-0.118	-0.740	<.001	<.001	3	10
SKIN	Circadian sleep/wake cycle →	+0.215	+1.034	<.001	<.001	3	9
BLOOD_Lymphoma	Vesicle coating →	+0.094	+1.554	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,249 associations by consensus.

Synaptic vesicle coating by AP3S2 expression — LIVER

Explore this box plot interactively →