AP3S1

Across TCGA patient cohorts, AP3S1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,280 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP3S1-associated genes across cancer lineages are MAN2A1, ATG12, and SRP19. Each is linked with AP3S1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP3S1-to-partner and partner-to-AP3S1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP3S1 versus MAN2A1 in OV, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3S1→partner) and Y-score (partner→AP3S1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MAN2A1 →	+0.758	+0.180	.001	.009	3	6
COAD	ATG12 →	+0.589	+0.235	<.001	<.001	3	5
COAD	SRP19 →	+0.408	+0.215	<.001	.002	3	5
OV	GLRX →	+0.695	+0.211	<.001	<.001	3	5
HNSC	TGIF2 →	-0.875	-0.217	<.001	<.001	3	4
OV	ELL2 →	+1.097	+0.256	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,280 associations by consensus.

AP3S1 vs MAN2A1 — OV

Explore this scatter interactively →