AP3M2

Across TCGA patient cohorts, AP3M2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,576 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible AP3M2-associated genes across cancer lineages are R3HCC1, RTN2, and RNF170. Each is linked with AP3M2 in more than 4 cancer types. Because this analysis shows association rather than direction, both AP3M2-to-partner and partner-to-AP3M2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP3M2 versus R3HCC1 in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3M2→partner) and Y-score (partner→AP3M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	R3HCC1 →	+0.495	+0.225	<.001	<.001	3	5
BRCA	RTN2 →	+1.083	+0.324	<.001	<.001	3	5
OV	RNF170 →	+0.618	+0.324	.001	<.001	3	5
LSCC	VDAC3 →	+0.789	+0.292	<.001	<.001	3	5
BRCA	POLB →	+0.822	+0.354	<.001	<.001	3	5
OV	KAT6A →	+0.776	+0.206	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,576 associations by consensus.

AP3M2 vs R3HCC1 — OV

Explore this scatter interactively →