AP3M2

Across TCGA cell cohorts, AP3M2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,808 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AP3M2-associated GO terms across cancer lineages are Clathrin-coated vesicle cargo loading, Clathrin-coated vesicle cargo loading, AP-3-mediated, and Positive regulation of cilium assembly. Each is linked with AP3M2 in more than 13 cancer types. Because this analysis shows association rather than direction, both AP3M2-to-partner and partner-to-AP3M2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Clathrin-coated vesicle cargo loading grouped by AP3M2-low versus AP3M2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3M2→partner) and Y-score (partner→AP3M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Clathrin-coated vesicle cargo loading →	+0.162	+1.223	<.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Clathrin-coated vesicle cargo loading, AP-3-mediated →	+0.162	+1.223	<.001	.003	3	14
BREAST	Positive regulation of cilium assembly →	+0.073	+1.109	.003	.001	2	14
UPPER_AERODIGESTIVE_TRACT	DNA biosynthetic process →	+0.072	+1.216	<.001	<.001	3	13
PANCREAS	Synaptic vesicle coating →	+0.165	+0.941	<.001	.003	3	12
UPPER_AERODIGESTIVE_TRACT	Microtubule anchoring at microtubule organizing center →	+0.083	+1.092	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,808 associations by consensus.

Clathrin-coated vesicle cargo loading by AP3M2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →