Across TCGA patient cohorts, AP3M1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,923 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP3M1-associated proteins across cancer lineages are KIFBP, DDX50, and GLRX3. Each is linked with AP3M1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AP3M1-to-partner and partner-to-AP3M1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3M1→partner) and Y-score (partner→AP3M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	KIFBP →	+0.259	+0.263	<.001	<.001	3	7
OV	DDX50 →	+0.359	+0.620	<.001	<.001	3	7
LSCC	GLRX3 →	+0.356	+0.392	<.001	<.001	3	7
LUAD	DDX21 →	+0.576	+0.347	<.001	<.001	3	6
GBM	WAPL →	+0.220	+0.384	<.001	<.001	3	6
UCEC	NHLRC2 →	+0.327	+0.420	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,923 associations by consensus.

Exploration

AP3M1 survival (RNA) · tumor vs normal (RNA) · all AP3M1 data types