Across TCGA patient cohorts, AP3M1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,868 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP3M1-associated genes across cancer lineages are DNAJC3, IL18R1, and SKP2. Each is linked with AP3M1 in more than 4 cancer types. Because this analysis shows association rather than direction, both AP3M1-to-partner and partner-to-AP3M1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3M1→partner) and Y-score (partner→AP3M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DNAJC3 →	+0.563	+0.190	.009	.003	3	5
UCEC	IL18R1 →	+0.932	+0.128	.003	.008	3	5
LSCC	SKP2 →	-0.935	-0.197	<.001	<.001	3	5
LSCC	TXNDC16 →	-0.720	-0.208	<.001	<.001	3	5
GBM	CENPV →	-1.171	-0.128	<.001	.001	3	5
LSCC	KLHL23 →	-1.239	-0.212	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,868 associations by consensus.

Exploration

AP3M1 survival (RNA) · tumor vs normal (RNA) · all AP3M1 data types