Across TCGA patient cohorts, AP3M1 mutation is significantly associated with the RNA expression of many other genes, with 633 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible AP3M1-associated genes across cancer lineages are TRAJ42, RN7SKP181, and RNU2-71P. Each is linked with AP3M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AP3M1-to-partner and partner-to-AP3M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3M1→partner) and Y-score (partner→AP3M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ42 →	+0.563	+2.284	<.001	.001	3	2
UCEC	RN7SKP181 →	+0.133	+2.870	<.001	.001	3	2
UCEC	RNU2-71P →	+0.240	+2.626	<.001	.002	3	2
UCEC	MTATP6P29 →	+0.166	+2.433	.007	.009	3	2
LUSC	MIR2115 →	+0.238	+4.882	.002	.005	3	2
BLCA	RNU6-756P →	+0.333	+7.640	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 633 associations by consensus.

Exploration

AP3M1 survival (RNA) · tumor vs normal (RNA) · all AP3M1 data types