Across TCGA cell cohorts, AP3M1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible AP3M1-associated genes across cancer lineages are CCL7, RXFP2, and CNMD. Each is linked with AP3M1 in more than 1 cancer types. Because this analysis shows association rather than direction, both AP3M1-to-partner and partner-to-AP3M1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3M1→partner) and Y-score (partner→AP3M1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CCL7 →	+0.491	+3.866	<.001	.006	3	1
LUNG_NSCLC_LUAD	RXFP2 →	+0.058	+4.959	<.001	<.001	3	1
LUNG_NSCLC_LUAD	CNMD →	+0.367	+3.807	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR52E8 →	+0.024	+4.681	<.001	.003	3	1
LUNG_NSCLC_LUAD	LILRA5 →	+0.030	+4.189	<.001	.002	3	1
LUNG_NSCLC_LUAD	SSX2 →	+1.170	+3.754	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

AP3M1 survival (RNA) · tumor vs normal (RNA) · all AP3M1 data types