AP3B2

Across TCGA patient cohorts, AP3B2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,774 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AP3B2-associated genes across cancer lineages are TMOD2, PDZD4, and RAB32. Each is linked with AP3B2 in more than 3 cancer types. Because this analysis shows association rather than direction, both AP3B2-to-partner and partner-to-AP3B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP3B2 versus TMOD2 in GBM, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3B2→partner) and Y-score (partner→AP3B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMOD2 →	+0.825	+0.670	<.001	<.001	3	4
HNSC	PDZD4 →	+1.921	+1.136	.001	.003	3	4
BRCA	RAB32 →	-0.624	-0.812	.005	.009	3	3
LSCC	OLFM1 →	+1.602	+0.532	.002	.003	3	3
BRCA	TES →	-1.195	-1.205	<.001	<.001	3	3
BRCA	RAB39B →	+0.808	+0.884	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,774 associations by consensus.

AP3B2 vs TMOD2 — GBM

Explore this scatter interactively →