AP3B1

Across TCGA patient cohorts, AP3B1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,991 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP3B1-associated genes across cancer lineages are VRK1, TAF5, and FANCB. Each is linked with AP3B1 in more than 6 cancer types. Because this analysis shows association rather than direction, both AP3B1-to-partner and partner-to-AP3B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP3B1 versus VRK1 in HNSC, with a Pearson correlation of -0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3B1→partner) and Y-score (partner→AP3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VRK1 →	-0.754	-0.125	.003	<.001	3	7
HNSC	TAF5 →	-0.535	-0.130	.001	<.001	3	6
LSCC	FANCB →	-0.975	-0.183	<.001	<.001	3	6
LSCC	KLHL23 →	-1.115	-0.163	<.001	<.001	3	6
HNSC	MAP4K5 →	-0.633	-0.118	.007	.001	3	5
BRCA	PM20D2 →	-1.314	-0.196	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,991 associations by consensus.

AP3B1 vs VRK1 — HNSC

Explore this scatter interactively →