AP3B1

Across TCGA cell cohorts, AP3B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,522 significant associations in total. BONE shows the largest number of these associations.

The most reproducible AP3B1-associated GO terms across cancer lineages are Dihydrofolate metabolic process, Protein localization to cytoskeleton, and Positive regulation of rRNA processing. Each is linked with AP3B1 in more than 10 cancer types. Because this analysis shows association rather than direction, both AP3B1-to-partner and partner-to-AP3B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Dihydrofolate metabolic process grouped by AP3B1-low versus AP3B1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP3B1→partner) and Y-score (partner→AP3B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Dihydrofolate metabolic process →	+0.203	+0.642	<.001	<.001	3	11
OVARY	Protein localization to cytoskeleton →	+0.053	+0.547	.004	.006	3	11
PANCREAS	Positive regulation of rRNA processing →	+0.114	+0.460	.002	.004	2	10
UPPER_AERODIGESTIVE_TRACT	Clathrin-coated vesicle cargo loading →	+0.123	+0.671	.002	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Clathrin-coated vesicle cargo loading, AP-3-mediated →	+0.123	+0.671	.002	<.001	3	9
BONE	Regulation of interleukin-6-mediated signaling pathway →	+0.308	+0.763	.002	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,522 associations by consensus.

Dihydrofolate metabolic process by AP3B1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →