AP2A2

Across TCGA patient cohorts, AP2A2 protein abundance is significantly associated with the RNA expression of many other genes, with 15,582 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible AP2A2-associated genes across cancer lineages are DAB2, ZCCHC24, and OLFML1. Each is linked with AP2A2 in more than 6 cancer types. Because this analysis shows association rather than direction, both AP2A2-to-partner and partner-to-AP2A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP2A2 versus DAB2 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP2A2→partner) and Y-score (partner→AP2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DAB2 →	+1.123	+0.277	<.001	<.001	3	7
OV	ZCCHC24 →	+1.267	+0.230	.001	<.001	3	7
BRCA	OLFML1 →	+0.633	+0.186	<.001	<.001	3	7
OV	PRKG1 →	+0.932	+0.293	<.001	<.001	3	7
LSCC	INMT →	+1.189	+0.243	<.001	<.001	3	7
HNSC	MEF2C →	+0.708	+0.184	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,582 associations by consensus.

AP2A2 vs DAB2 — OV

Explore this scatter interactively →