Across TCGA patient cohorts, AP2A1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,968 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible AP2A1-associated proteins across cancer lineages are SCRN2, PPP5C, and PRMT1. Each is linked with AP2A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AP2A1-to-partner and partner-to-AP2A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP2A1→partner) and Y-score (partner→AP2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SCRN2 →	-0.325	-0.340	.001	<.001	3	4
GBM	PPP5C →	+0.236	+0.256	<.001	<.001	3	3
LSCC	PRMT1 →	+0.235	+0.397	<.001	.001	2	4
LUAD	RPS6KA3_T365 →	-0.408	-0.397	<.001	<.001	3	3
OV	SEC23A →	+0.325	+0.553	<.001	.008	3	3
OV	SFRP2 →	+1.314	+0.785	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,968 associations by consensus.

Exploration

AP2A1 survival (RNA) · tumor vs normal (RNA) · all AP2A1 data types