AP2A1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, AP2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,631 significant associations in total. CNS shows the largest number of these associations.

The most reproducible AP2A1-associated GO terms across cancer lineages are Negative regulation of hyaluronan biosynthetic process, Retrograde transport, endosome to Golgi, and Endosomal transport. Each is linked with AP2A1 in more than 17 cancer types. Because this analysis shows association rather than direction, both AP2A1-to-partner and partner-to-AP2A1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP2A1→partner) and Y-score (partner→AP2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIVERNegative regulation of hyaluronan biosynthetic process →+0.321+1.036<.001<.001318
BONERetrograde transport, endosome to Golgi →+0.071+1.081<.001<.001318
BONEEndosomal transport →+0.082+1.288<.001<.001317
UPPER_AERODIGESTIVE_TRACTCytosolic transport →+0.064+0.878.001.001316
UPPER_AERODIGESTIVE_TRACTNegative regulation of calcium ion export across plasma membrane →+0.075+1.008<.001<.001315
SOFT_TISSUEResponse to dehydroepiandrosterone →+0.218+1.009<.001<.001314
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,631 associations by consensus.

Exploration