AP1S3

Across TCGA patient cohorts, AP1S3 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. COAD shows the largest number of these associations.

The most reproducible AP1S3-associated genes across cancer lineages are Monocytes and Mesangial cells. Each is linked with AP1S3 in more than 1 cancer types. Because this analysis shows association rather than direction, both AP1S3-to-partner and partner-to-AP1S3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by AP1S3-low versus AP1S3-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1S3→partner) and Y-score (partner→AP1S3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Monocytes →	+0.028	+4.734	<.001	.045	3	1
SKCM	Mesangial cells →	+0.009	+3.290	.033	.044	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Monocytes by AP1S3 expression — COAD

Explore this box plot interactively →