AP1M2

Across TCGA cell cohorts, AP1M2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,446 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible AP1M2-associated GO terms across cancer lineages are Basolateral protein secretion, Positive regulation of blood-brain barrier permeability, and Response to indole-3-methanol. Each is linked with AP1M2 in more than 9 cancer types. Because this analysis shows association rather than direction, both AP1M2-to-partner and partner-to-AP1M2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Basolateral protein secretion grouped by AP1M2-low versus AP1M2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1M2→partner) and Y-score (partner→AP1M2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Basolateral protein secretion →	+0.210	+3.674	<.001	<.001	3	10
PANCREAS	Positive regulation of blood-brain barrier permeability →	+0.344	+2.566	.006	.001	3	10
PANCREAS	Response to indole-3-methanol →	+0.208	+3.810	<.001	<.001	3	10
STOMACH	Bundle of His cell to Purkinje myocyte communication →	+0.264	+2.568	<.001	<.001	3	10
OVARY	Establishment of epithelial cell apical/basal polarity →	-0.165	-2.468	<.001	<.001	3	10
OVARY	Positive regulation of collagen biosynthetic process →	-0.151	-2.413	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,446 associations by consensus.

Basolateral protein secretion by AP1M2 expression — STOMACH

Explore this box plot interactively →