Across TCGA patient cohorts, AP1G2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,126 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AP1G2-associated genes across cancer lineages are FXYD6, DCLK2, and MPPED2. Each is linked with AP1G2 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP1G2-to-partner and partner-to-AP1G2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1G2→partner) and Y-score (partner→AP1G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FXYD6 →	-1.575	-0.385	<.001	<.001	3	6
GBM	DCLK2 →	-0.809	-0.325	<.001	<.001	3	5
GBM	MPPED2 →	-1.358	-0.408	<.001	<.001	3	5
UCEC	CORO2A →	+0.906	+0.327	<.001	<.001	3	5
LSCC	TEP1 →	+0.488	+0.338	<.001	<.001	3	5
GBM	TNFSF13 →	+0.730	+0.376	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,126 associations by consensus.

Exploration

AP1G2 survival (RNA) · tumor vs normal (RNA) · all AP1G2 data types