Across TCGA cell cohorts, AP1G2 mutation is significantly associated with the RNA expression of many other genes, with 82 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible AP1G2-associated genes across cancer lineages are CCN4, ARMS2, and UBQLN3. Each is linked with AP1G2 in more than 1 cancer types. Because this analysis shows association rather than direction, both AP1G2-to-partner and partner-to-AP1G2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1G2→partner) and Y-score (partner→AP1G2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CCN4 →	+0.052	+3.504	<.001	.009	3	1
BLOOD_Leukemia	ARMS2 →	+0.021	+3.507	<.001	.004	3	1
LUNG_NSCLC_LUAD	UBQLN3 →	+0.006	+4.734	.002	.002	3	1
LARGE_INTESTINE	RBFA →	+0.775	+3.212	.002	.006	3	1
LARGE_INTESTINE	RFPL2 →	+0.160	+3.292	<.001	.004	3	1
LARGE_INTESTINE	TYW3 →	+0.650	+3.212	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 82 associations by consensus.

Exploration

AP1G2 survival (RNA) · tumor vs normal (RNA) · all AP1G2 data types