AP1G1

Across TCGA patient cohorts, AP1G1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,442 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible AP1G1-associated genes across cancer lineages are IST1, GOT2, and MVD. Each is linked with AP1G1 in more than 7 cancer types. Because this analysis shows association rather than direction, both AP1G1-to-partner and partner-to-AP1G1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP1G1 versus IST1 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1G1→partner) and Y-score (partner→AP1G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IST1 →	+0.636	+0.294	<.001	<.001	3	8
BRCA	GOT2 →	+0.610	+0.270	<.001	<.001	3	7
UCEC	MVD →	+1.008	+0.214	<.001	<.001	3	7
OV	CMTR2 →	+0.750	+0.279	<.001	.001	3	7
LSCC	MEAK7 →	+0.748	+0.161	<.001	<.001	3	6
OV	CFDP1 →	+0.801	+0.390	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,442 associations by consensus.

AP1G1 vs IST1 — OV

Explore this scatter interactively →