AP1G1

Across TCGA cell cohorts, AP1G1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,371 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AP1G1-associated GO terms across cancer lineages are mRNA export from nucleus, Viral transcription, and Promoter clearance during DNA-templated transcription. Each is linked with AP1G1 in more than 17 cancer types. Because this analysis shows association rather than direction, both AP1G1-to-partner and partner-to-AP1G1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA export from nucleus grouped by AP1G1-low versus AP1G1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1G1→partner) and Y-score (partner→AP1G1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA export from nucleus →	+0.118	+1.105	<.001	<.001	3	18
STOMACH	Viral transcription →	+0.141	+0.991	<.001	.002	3	18
KIDNEY	Promoter clearance during DNA-templated transcription →	+0.198	+1.036	<.001	<.001	3	18
KIDNEY	RNA polymerase II promoter clearance →	+0.198	+1.036	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	mRNA transport →	+0.112	+0.907	<.001	<.001	3	18
KIDNEY	Nucleic acid transport →	+0.098	+0.884	<.001	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,371 associations by consensus.

mRNA export from nucleus by AP1G1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →