AP1B1

Across TCGA patient cohorts, AP1B1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,237 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AP1B1-associated proteins across cancer lineages are CBX8, CORO1A, and DOCK2. Each is linked with AP1B1 in more than 3 cancer types. Because this analysis shows association rather than direction, both AP1B1-to-partner and partner-to-AP1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP1B1 versus CBX8 in GBM, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1B1→partner) and Y-score (partner→AP1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CBX8 →	-0.468	-0.508	<.001	<.001	3	4
OV	CORO1A →	+0.651	+0.720	.002	.005	3	4
GBM	DOCK2 →	+0.689	+0.570	<.001	<.001	3	4
GBM	IFI30 →	+0.759	+0.496	<.001	<.001	3	4
GBM	APOBR →	+0.595	+0.502	<.001	<.001	3	4
CCRCC	MSR1_S27 →	+0.859	+0.398	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,237 associations by consensus.

AP1B1 vs CBX8 — GBM

Explore this scatter interactively →