AP1B1

Across TCGA patient cohorts, AP1B1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,393 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible AP1B1-associated genes across cancer lineages are ASXL1, C18orf54, and ZNF286A. Each is linked with AP1B1 in more than 5 cancer types. Because this analysis shows association rather than direction, both AP1B1-to-partner and partner-to-AP1B1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AP1B1 versus ASXL1 in LUAD, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1B1→partner) and Y-score (partner→AP1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ASXL1 →	-0.460	-0.138	.001	.003	3	6
LSCC	C18orf54 →	-0.689	-0.137	<.001	<.001	3	5
LSCC	ZNF286A →	-0.598	-0.144	<.001	<.001	3	5
UCEC	OBSCN →	-0.624	-0.196	.003	.001	3	5
LSCC	MEX3A →	-1.224	-0.171	<.001	<.001	3	5
GBM	MS4A6A →	+0.874	+0.161	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,393 associations by consensus.

AP1B1 vs ASXL1 — LUAD

Explore this scatter interactively →