AP1B1

Across TCGA cell cohorts, AP1B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,369 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible AP1B1-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and DNA replication-dependent chromatin assembly. Each is linked with AP1B1 in more than 16 cancer types. Because this analysis shows association rather than direction, both AP1B1-to-partner and partner-to-AP1B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by AP1B1-low versus AP1B1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1B1→partner) and Y-score (partner→AP1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.136	+0.755	<.001	.003	3	17
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.136	+0.755	<.001	.003	3	17
OVARY	DNA replication-dependent chromatin assembly →	+0.114	+0.736	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of Golgi inheritance →	+0.199	+0.882	.001	.002	3	14
LARGE_INTESTINE	Negative regulation of chromosome condensation →	+0.138	+0.779	<.001	<.001	3	14
BLOOD_Lymphoma	P-body assembly →	+0.099	+1.054	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,369 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by AP1B1 expression — BREAST

Explore this box plot interactively →