AP1AR

Across TCGA pan-cancer cohorts, AP1AR mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated AP1AR data layer compared with 27 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher AP1AR mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated AP1AR expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, HNSC, and PDAC are the cancer types where AP1AR mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	0.834	0.633	.005	38	view →
HNSC	DFS	Quartile	III,IV	0.744	1.000	.023	8	view →
PDAC	OS	Quartile	III,IV	0.311	0.835	.038	5	view →
LSCC	DFS	Tertile	All	0.365	1.000	.013	4	view →
GBM	OS	Median	All	0.837	0.934	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

AP1AR–CCRCC (DFS)

Open the CCRCC breakdown →