AP1AR

Across TCGA cell cohorts, AP1AR RNA expression is significantly associated with the go_rna of many other GO terms, with 4,018 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible AP1AR-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Negative regulation of receptor recycling, and Apoptotic cell clearance. Each is linked with AP1AR in more than 10 cancer types. Because this analysis shows association rather than direction, both AP1AR-to-partner and partner-to-AP1AR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by AP1AR-low versus AP1AR-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (AP1AR→partner) and Y-score (partner→AP1AR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.173	+0.860	<.001	<.001	3	11
URINARY_TRACT	Negative regulation of receptor recycling →	+0.208	+0.931	<.001	<.001	3	11
LARGE_INTESTINE	Apoptotic cell clearance →	-0.174	-0.935	<.001	<.001	3	11
SOFT_TISSUE	Double-strand break repair via nonhomologous end joining →	+0.040	+0.691	.008	.002	3	11
LIVER	Oocyte growth →	+0.219	+0.827	.001	.002	3	11
BONE	mRNA destabilization →	+0.062	+0.936	.005	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,018 associations by consensus.

Negative regulation of chromosome condensation by AP1AR expression — SOFT_TISSUE

Explore this box plot interactively →