Q-omics provides the consensus-scored AOX3P profile across patient tissues and cancer cell-line models. AOX3P expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, AOX3P is differentially expressed in 8, with the highest sampling consensus in KICH. Additionally, AOX3P RNA expression shows 13,525 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight MESO, KICH, and GBM as cancer lineages where AOX3P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for AOX3P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes AOX3P survival associations across molecular data types. AOX3P RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible AOX3P RNA expression–survival associations across cancer types. High AOX3P expression shows unfavorable associations in BLCA, LGG, CHOL and READ, but favorable associations in MESO and PAAD. The MESO Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for AOX3P RNA expression.
This table summarizes AOX3P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for AOX3P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. AOX3P shows lower tumor expression in KICH, LUSC, BRCA and COAD and higher tumor expression in LIHC and KIRC. The KICH box plot shows higher AOX3P RNA expression in normal versus tumor tissue (log2 FC = −0.012, t-test p < 0.001).
This table shows molecular features associated with AOX3P in patient tissues and cancer cell lines. In patient samples, AOX3P shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
