AOX2P

Across TCGA patient cohorts, AOX2P mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. CESC shows the largest number of these associations.

The most reproducible AOX2P-associated genes across cancer lineages are FAM197Y9, OR4A47, and OR2A41P. Each is linked with AOX2P in more than 1 cancer types. Because this analysis shows association rather than direction, both AOX2P-to-partner and partner-to-AOX2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM197Y9 grouped by AOX2P-low versus AOX2P-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AOX2P→partner) and Y-score (partner→AOX2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	FAM197Y9 →	+0.019	+6.144	<.001	.001	3	1
CESC	OR4A47 →	+0.039	+5.201	<.001	.007	3	1
CESC	OR2A41P →	+0.378	+7.584	<.001	<.001	3	1
CESC	RPL31P59 →	+0.180	+5.010	<.001	.009	3	1
CESC	DUXAP6 →	+0.213	+5.969	<.001	.002	3	1
CESC	MIR3126 →	+0.667	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

FAM197Y9 by AOX2P expression — CESC

Explore this box plot interactively →