AOAH

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, AOAH protein abundance is significantly associated with the RNA expression of many other genes, with 13,495 significant associations in total. GBM shows the largest number of these associations.

The most reproducible AOAH-associated genes across cancer lineages are CSF2RB, STX11, and RGS18. Each is linked with AOAH in more than 7 cancer types. Because this analysis shows association rather than direction, both AOAH-to-partner and partner-to-AOAH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, AOAH versus CSF2RB in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (AOAH→partner) and Y-score (partner→AOAH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCSF2RB →+1.249+0.698<.001<.00138
GBMSTX11 →+0.708+0.464<.001<.00138
GBMRGS18 →+0.880+0.512<.001<.00138
HNSCCTLA4 →+1.125+0.508<.001<.00138
GBMSELL →+1.406+0.450<.001<.00138
GBMPTPRC →+1.181+0.678<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,495 associations by consensus.

AOAH vs CSF2RB — GBM

Per-sample scatter of AOAH vs CSF2RB in GBM (Pearson r = 0.69).

Explore this scatter interactively →

Exploration