ANXA9

Across TCGA patient cohorts, ANXA9 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA9-associated genes across cancer lineages are ATM, eIF4E, and Src. Each is linked with ANXA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA9-to-partner and partner-to-ANXA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by ANXA9-low versus ANXA9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA9→partner) and Y-score (partner→ANXA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.644	-2.415	<.001	.003	3	2
SKCM	eIF4E →	+0.211	+3.169	.028	.019	2	2
SKCM	Src →	-0.284	-3.169	.023	.019	3	1
SKCM	Stathmin →	+0.218	+3.169	.024	.019	3	1
UCEC	EGFR_pY1068 →	-0.237	-2.415	.018	.003	3	1
UCEC	GAPDH →	+0.438	+1.906	.042	.016	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

ATM by ANXA9 expression — UCEC

Explore this box plot interactively →