ANXA9

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANXA9 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANXA9-associated genes across cancer lineages are AVP, NKX2-6, and TLE7. Each is linked with ANXA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA9-to-partner and partner-to-ANXA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by ANXA9-low versus ANXA9-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA9→partner) and Y-score (partner→ANXA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaAVP →+0.031+5.209<.001.00531
BLOOD_LeukemiaNKX2-6 →+0.591+5.201<.001.00631
BLOOD_LeukemiaTLE7 →+0.042+5.969<.001.00131
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

AVP by ANXA9 expression — BLOOD_Lymphoma

Box plot of AVP in ANXA9-low vs ANXA9-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration