Across TCGA patient cohorts, ANXA6 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA6-associated genes across cancer lineages are eEF2, eIF4E, and MEK1. Each is linked with ANXA6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ANXA6-to-partner and partner-to-ANXA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA6→partner) and Y-score (partner→ANXA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.319	+1.662	.011	.011	3	3
UCEC	eIF4E →	+0.180	+3.183	.015	.009	3	2
COAD	MEK1 →	+0.391	+3.484	<.001	.002	3	2
UCEC	MSH2 →	-0.202	-1.973	.013	.029	3	2
UCEC	Notch1 →	+0.216	+2.392	<.001	<.001	3	2
COAD	PCNA →	+0.315	+3.467	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

Exploration

ANXA6 survival (RNA) · tumor vs normal (RNA) · all ANXA6 data types