ANXA6

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANXA6 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ANXA6-associated genes across cancer lineages are FCRL5, CD1A, and SCARA5. Each is linked with ANXA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA6-to-partner and partner-to-ANXA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA6→partner) and Y-score (partner→ANXA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEFCRL5 →+0.069+3.421<.001.00831
LARGE_INTESTINECD1A →+0.017+3.084.005.00231
LARGE_INTESTINESCARA5 →+0.320+3.362.002.00731
LARGE_INTESTINEGPR171 →+0.020+3.425<.001<.00131
LARGE_INTESTINEZNF366 →+0.019+3.240<.001.00431
LARGE_INTESTINECCL18 →+0.050+3.678.003.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration