ANXA4

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ANXA4 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible ANXA4-associated genes across cancer lineages are XCL2, COX4I2, and OR2K2. Each is linked with ANXA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA4-to-partner and partner-to-ANXA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA4→partner) and Y-score (partner→ANXA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASXCL2 →+0.237+4.011<.001.00932
LIVERCOX4I2 →+0.045+3.662<.001.00531
LIVEROR2K2 →+0.034+3.662<.001.00531
LIVERWFDC10A →+0.157+3.662<.001.00531
LIVERC1QTNF8 →+0.020+3.662.003.00531
LIVERCD300LF →+0.252+3.584<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration