ANXA3

Across TCGA patient cohorts, ANXA3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,800 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ANXA3-associated genes across cancer lineages are CXCL8, SLPI, and PROK2. Each is linked with ANXA3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ANXA3-to-partner and partner-to-ANXA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ANXA3 versus CXCL8 in GBM, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA3→partner) and Y-score (partner→ANXA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXCL8 →	+2.275	+1.362	<.001	<.001	3	7
BRCA	SLPI →	+1.978	+0.631	<.001	<.001	3	6
HNSC	PROK2 →	+1.019	+0.734	<.001	<.001	3	6
OV	MET →	+1.231	+0.771	.001	<.001	3	5
OV	VWA5A →	+0.952	+0.957	.002	<.001	3	5
LUAD	TSPAN1 →	+1.835	+0.642	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,800 associations by consensus.

ANXA3 vs CXCL8 — GBM

Explore this scatter interactively →