ANXA2P3

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ANXA2P3 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ANXA2P3-associated genes across cancer lineages are EGFR_pY1068, ERK2, and p62 Lck ligand. Each is linked with ANXA2P3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ANXA2P3-to-partner and partner-to-ANXA2P3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ANXA2P3→partner) and Y-score (partner→ANXA2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.278-2.321.011.03431
UCECERK2 →+0.197+2.115.019.01931
UCECp62 Lck ligand →+0.302+2.115.033.01931
UCECPI3K-p85 →+0.193+1.884.034.03031
UCECAnnexin-1 →+0.566+3.019.013.01931
UCECCaspase-7-cleavedD198 →+0.778+3.479.002.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration